Research Library
Browse all evidence-based content: herbs, supplements, conditions, and clinical topics. Use the filter to narrow by content type.
Aging & Longevity
Longevity science has advanced dramatically, identifying cellular mechanisms of aging including telomere shortening, epigenetic ch...
Ashwagandha
Ashwagandha is an adaptogenic herb with the strongest clinical evidence for reducing perceived stress, lowering cortisol, and impr...
Autoimmune Disorders
Autoimmune disorders involve immune system dysregulation where the body attacks its own tissues. Over 80 recognized conditions aff...
Berberine
Berberine is an alkaloid compound found in barberry, goldenseal, and Oregon grape with some of the strongest human clinical eviden...
Boswellia
Boswellia is a tree resin sold for joint health. Small human studies suggest that some oral extracts may ease knee osteoarthritis ...
Chronic Inflammation
Chronic low-grade inflammation underlies most major diseases including cardiovascular disease, type 2 diabetes, cancer, and neurod...
CoQ10 (Coenzyme Q10)
CoQ10 is an endogenous antioxidant and critical component of mitochondrial energy production. Evidence supports supplementation fo...
Curcumin
Curcumin is the primary bioactive compound in turmeric with extensive research on anti-inflammatory and antioxidant effects. Multi...
Echinacea
Echinacea is one of the most widely used herbs for immune support, with a large clinical evidence base. Meta-analyses suggest mode...
Gut Health
Gut health encompasses intestinal barrier integrity, gut microbiome diversity, digestive function, and gut-brain axis communicatio...
Immune Modulation
Immune modulation means changing how an immune response works, not simply making it stronger. The right question is which response...
Irritable Bowel Syndrome (IBS)
IBS is a functional gastrointestinal disorder affecting 10-15% of the population. Multiple natural approaches have clinical eviden...
Japanese Knotweed
Japanese knotweed contains resveratrol and other plant compounds. Its extract has been tested against Lyme disease bacteria in a l...
Long COVID (Post-COVID Syndrome)
Long COVID (post-COVID syndrome) refers to symptoms persisting 12 or more weeks after acute COVID-19 infection. Research is rapidl...
Lyme Disease
Lyme disease is a tick-borne bacterial infection caused by Borrelia burgdorferi. Standard treatment is antibiotic therapy and is h...
Magnesium
Magnesium is an essential mineral cofactor in over 300 enzymatic reactions. Suboptimal intake is extremely common in Western popul...
Mitochondrial Health
Mitochondria are the primary energy-producing organelles of every cell. Mitochondrial dysfunction is increasingly recognized as a ...
NAC (N-Acetylcysteine)
NAC is a form of the amino acid cysteine that the body can use to make glutathione. Prescription acetylcysteine has established me...
Omega-3 Fatty Acids
Omega-3 fatty acids (EPA and DHA) have some of the strongest evidence among supplements for cardiovascular risk reduction, triglyc...
Probiotics
Probiotics are live microorganisms with a large and growing evidence base. Strongest evidence supports use for antibiotic-associat...